What is an endometrial biopsy?

An endometrial biopsy (EMB) is an in-office procedure that is usually done to gain more information about the uterine lining or endometrium. An EMB can help determine if there are certain factors present which are associated with infertility, such as a chronic infection, polyps, endometrial hyperplasia, and endometrial cancer. Not all women with infertility require this procedure. EMB may be suggested for women who have a history of amenorrhea or not having periods for long periods of time, women with prolonged exposure to unopposed estrogen, or some women with polycystic ovarian syndrome (PCOS).

A urine pregnancy test is typically done prior to the EMB. A speculum exam is performed and the cervix is cleansed with either betadine, hibiclens, or saline. A small catheter is then passed through the cervix into the uterus to sample cells of the endometrial lining. This can cause some cramping; taking acetaminophen or Ibuprofen 1 hour prior to the procedure is often recommended. The biopsy sample is then sent to the lab for evaluation. Any discomfort felt during the procedure is short-lived, and most women are able to return to their usual activities immediately after the biopsy is complete.

Our patients will meet with our physicians to determine if an EMB is necessary prior to fertility treatment. For more information regarding EMB, please schedule an appointment with one of our providers at the Fertility Institute of Hawaii 808-545-2800 or visit our website at https://www.ivfcenterhawaii.com.

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