The Endometrial Lining


As promised, each Thursday, we will now offer you a piece of educational, science, or research related information. The purpose of our #ThursdayThoughts post is to share with you fact-based content that can enlighten and assist you on your fertility journey. Enjoy our post! Helping to Create New Beginnings….

The Endometrial Lining

Fertility is more than the eggs and sperm: The Endometrial Lining

There are a lot of different things that can impact fertility. One important part of the process involves the endometrial lining. This is the lining of the uterus that the embryo will implant into.  The lining of the uterus sheds during each menstrual cycle and is replaced by new cells. There is good research that shows that during times of injury the body sends stem cells from the bone marrow to help regenerate the endometrial cells. Stem cells are undifferentiated cells that can often regenerate tissue.  In certain settings where there is low estrogen or significant injury this process may be impaired. If we can study the biology of stem cells and their role in this process, as well as how to improve the transport of the stem cells to the uterus we may be able to help treat endometrial receptivity defects more effectively. There are a number of tests and treatments that can be utilized to diagnose and potentially treat problems with the uterine lining. Special imaging techniques, such as a saline sonohysterogram, can determine if any lesions within the uterus (such as polyps, fibroids, or abnormal uterine shapes) might contribute to infertility. Tests such as the Endometrial Receptivity Assay (ERA) can be used in patients who have been unsuccessful with in vitro fertilization. To learn more about tests and treatments for uterine lining issues, please call the Fertility Institute of Hawaii at 808-545-2800 to schedule an appointment, or visit our website at 

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